Endocrine Abstracts

Hemoglobin A1c (HbA1c) has been used as a clinically significant evaluation tool for analyses regarding glycemic control. Guidelines recommend patients with type 2 diabetes mellitus (T2DM) should aim for an A1C≤7.0%, but real world data is limited in the elderly regarding outcomes associated with different A1C levels.A thousand six hundred Turkish cases were enrolled in this study. The mean age of the patients was 57 (17 to 91) years. The mean HbA1...

Introduction: Brown tumor is a rare benign bone lesion with incidence ranging from 1.5% in primary hyperparathyroidism to 13% in secondary hyperparathyroidism. Common sites of involvement are pelvis, femur and ribs, but may appear in any bone. Since the incidence of thyroid disease is higher among patients with hyperparathyroidism than the general population, these lesions must be distinguished from metastases from thyroid carcinoma.We present a patient ...

Background: Our aim was to investigate levels of lipocalin-2 and its relationship with metabolic factors in women with polycystic ovary syndrome (PCOS).Materials/subjects and methods: In this cross-sectional study, two groups of women were studied: group 1 consisted of women with PCOS (n=30), and group 2 consisted of control women with normal ovulatory function (n=30). The circulating levels of lipocalin were measured.<p class="abstext"...

Aim: Currently, imaging tools are increasing the frequency of thyroid nodules to 50%, and thyroid cancer risk is 7-15%. The most cost-effective, accurate diagnosis method is fine-needle aspiration biopsy (FNAB). However, non-diagnostic (ND) results can delay diagnosis, cause different procedures, raise costs, and distress patients. In addition, FNAB sample adequacy is affected by advanced age, nodule size (<5-10mm), cystic dominating nodules, macrocalcification, and hypo-e...

Context: Polycystic ovary syndrome (PCOS) is a common and complex endocrine disorder. Emerging animal and human data point out to various changes in microbiota that could be linked with the syndrome. However, the effects of therapeutic approaches on gut microbial composition in women with PCOS remain unknown.Objective: We aimed to assess whether gut microbial composition is altered in overweight/obese women with PCOS and to determine potential impact of ...

Background: Generously supported by IPSEN)-->In this study we have aimed to calculate the QT dispersion in acromegaly patients and reveal its correlation with GH and IGF1.Materials and methods: Forty-one acromegaly patients were enrolled in the study. Another 41 patients with similar age, sex and comorbid disease distrubition have constituted the control group. We have evaluated the electrocardiograms (ECG) of ...

Introduction: The clinical implications of QTc and P wave dispersion in patients with Cushing’s syndrome have not been studied previously. In this study, we aimed to compare QTc dispersion and P wave dispersion in patients with Cushing’s syndrome and healthy subjects.Material and method: Sixteen patients with Cushing’s syndrome diagnosed on clinical, laboratory and imaging findings and 16 age and sex matched control subjects were included....

Introduction: Serum thyroid hormone levels have been described in several systemic non-thyroideal illnesses, among them acute heart diseases. The aim of this study was to investigate the relationship between thyroid functions and widespread of ACS, and to evaluate the potential changes in thyroid hormone profile in acute coronary syndromes (ACS) at the time of diagnosis and compare them between two groups, based on therapeutic implications and distinct prognoses: unstable angi...

Objective: Our aim was to evaluate C-reactive protein (CRP) and serum vaspin levels in women with polycystic ovary syndrome (PCOS) or polycystic ovaries (PCO).Design: Twenty-four women with PCOS and 23 women with PCO constituted the study groups. The control group comprised 24 healthy women.Methods: Homeostatic model assessment for insulin resistance (HOMA-IR), CRP and serum vaspin levels were measured. The receiver operating chara...

Objective: The status of carbohydrate metabolism of pregnant women with positive glucose challenge test (GCT), but normal oral glucose tolerance test (OGTT); and their neonates have not defined clearly.Methods: Pregnant women with normal GCT (n: 120), with abnormal glucose challenge test (AGCT) but normal OGTT (n: 67) and those with gestational diabetes (GDM) (n: 67) were included into the study. Local ethical committee approval was ...